Dr. Christopher was given the formula from Efret. Dr. Christopher tweaked the formula so people would not "feel" a gripping sensation. He took o much cayenne that "he" couldn't feel that there was too much cayenne for the normal average person. So I adjusted that until women quit complaining and added Olive Leaf.
Shulse and others took the same concept and added more cayenne, more laxative type herbs and even damageing herbs.
I 100% believe the original with a minor ajustment to the cayenne as being the absolute best when taken as Dr. Christopher instructed, which basically was 8 capsules daily for 9 months and then adjust your dose based on your health situation. I believe after a few years, the normal person eating the normal diet, needs 1 bottle of 550 per year.
Naturally de-worming is a huge part of colon health, so I suggest de-worming as part of the larger program.