Re: Scientists cure cancer, but no one takes notice

Mitochondria are the part of the cell where energy is produced (ATP, Kreb's cycle), also the part of the cell that determines when cell death accurs (Apoptosis).

Dichloroacetate (DCA) downregulates an enzyme in the mitochonria called Pyruvate Dehydrogenase Kinase (PDK) which will result in tumor shrinkage. But, it is toxic. There are many natural substances that inhibit PDK:


Natural inhibitors of pyruvate dehydrogenase kinase:

*R+ Alpha lipoic acid (natural form) 100 to 150 mg 3 times daily, best in a time-release carrier.

B1 or thiamine, especially as the fat-soluble benfotiamine 80 to 160 mg 2 times daily.

Other natural agents which evidence suggests will activate the mitochondria to turn off cancer cells:

*L-carnitine -a potent mitochondria booster, but needs ALA to regulate the ROS created.

*Omega 3 marine source oils assist in membrane repolarization and stabilization.

*Gamma tocopherol (mixed tocopherols or vitamin E) – 400 to 800 IU daily traps peroxynitrite radicals.

Further remedies for mitochondrial reactivation:

L-glutamine - glutamine is the primary mitochondrial substrate and is required for maintenance of mitochondrial membrane potential and integrity and for support of the NADPH production needed for redox control and macromolecular synthesis. It can be manufactured from glucose.

Coenzyme Q10 - 100 mg 3 times daily – absorbs best when taken with fats or oils

Quercitin (with bromelain for absorption) - 2 capsules 2 to 3 times daily

Grapeseed extract (oligomeric proanthocyanidins) – 100 mg 3 times daily

Ganoderma lucidum (Reishi) mushroom extract - 500 to 1,000 mg 3 times daily

Indole-3-carbinol 200 mg 2 to 3 times daily

Ellagic acid – can be as 8 ounces of unsweetened pomegranate, grape or berry juices

Betulinic acid from birch leaves 20 to 40 mg/Kg/day.

B-vitamins riboflavin (B2) and niacin (B3) as nicotinamide - 50 to 100 mg 2 to 3 times daily

http://en.wikipedia.org/wiki/Mitochondrion

http://en.wikipedia.org/wiki/Pyruvate_dehydrogenase_kinase

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