"A pyrrole is a chemical substance that is involved in the formation of heme, which makes blood red. Pyrroles bind with B₆ and then with zinc, thus depleting these nutrients. Abnormal production of pyrroles and their appearance in the urine of psychotics was first noticed in 1958 during LSD experimentation. Approximately 15-30% of "schizophrenics" have pyroluria. (At least 10% of these also have histamine problems.)

Symptoms include sweet, fruity breath and body odor, general loss of appetite, motion sickness, problems with sugar metabolism, allergies. Mental phenomena include delusions, hallucinations, paranoia, occasional loss of contact with reality, amnesia spells, and low stress tolerance. Person has a tendency to have insight (understand they have mental problems).

The ailment, which normally strikes females, generally responds well to B₆ and zinc treatment."

That was from the url above and if you google it there's a lot more info.