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T cell CAEBV- is more fatal than NK cell virus.
 
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Published: 13 y
 

T cell CAEBV- is more fatal than NK cell virus.


bloodjournal.hematologylibrary.org/cgi/content/full/98/2/280

Thirty patients with chronic active Epstein-Barr virus (CAEBV) infection were analyzed. The study group included 18 male and 12 female patients, ranging in age from 5 to 31 years with a mean age of 14.2 years. Not all patients had high titers of EBV-specific antibodies, but all patients had high viral loads in their peripheral blood (more than 102.5 copies/µg DNA). Fifty percent of the patients displayed chromosomal aberrations, and 79% had monoclonality of EBV. Patients were divided into 2 clinically distinct groups, based on whether the predominantly infected cells in their peripheral blood were T cells or natural killer (NK) cells. Over a 68-month period of observation, 10 patients died from hepatic failure, malignant lymphoma, or other causes. Patients with T-cell CAEBV had a shorter survival time than those with NK-cell type of disease. (Blood. 2001;98:280-286)

© 2001 by The American Society of Hematology.

Here's another ladies story who died of T cell CAEBV.

www.pdfdownload.org/pdf2html/pdf2html.php

 

 
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