Mediterranean diet or extended fasting's influence on changing the intestinal microflora, immunoglobulin A secretion and clinical outcome in patients with rheumatoid arthritis symptoms and fibromyalgia: an observational study
Results: We found no significant alterations in the fecal bacterial counts following a two dietary interventions within and between groups, nor were significant differences based in the analysis of sIgA and stool ph. Clinical improvement at the conclusion from the hospital stay were rather greater in fasting vs. non-fasting patients with RA (p = 0.09). Clinical outcome wasn't associated with modifications in the intestinal flora.
Conclusion: Neither Mediterranean diet nor fasting treatments impact microbiologically assessed intestinal flora and sIgA levels in sufferers with RA and FM. The impact of nutritional interventions in the human intestinal flora and also the role of the bowel flora in rheumatic diseases need to be clarified with newer molecular analysis techniques. The possibility advantage of fasting treatment in RA and FM ought to be further tested in randomised trials.