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Re: Chronic Sinusitis: Anti-fungal Sinus Spray?
 
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Published: 15 y
 
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Re: Chronic Sinusitis: Anti-fungal Sinus Spray?


Whatever you choose (there's a great olive leaf one on the market also, very gentle) - apparently adding a drop of baby shampoo will disrupt the biofilm which protects the fungi/molds/bacteria. Biofilm created by these organisms is the primary cause for (pharmal or natural) anti-fungal or anti-biotic resistant infections.

Baby shampoo cantains a zwitterionic surfactant, which disrupts this. See study below and/or google .

http://www.ncbi.nlm.nih.gov/pubmed/17883887


Methods for removing bacterial biofilms: in vitro study using clinical chronic rhinosinusitis specimens.
Desrosiers M, Myntti M, James G.

Abstract
BACKGROUND: Bacterial biofilms may be involved in refractory chronic rhinosinusitis (CRS). In vitro, we studied methods for removing biofilms formed by Staphylococcus aureus and Pseudomonas aeruginosa.

METHODS: Bacterial isolates were obtained from patients with refractory CRS and were plated and treated with either static administration of citric acid /zwitterionic surfactant (CAZS), saline delivered with hydrodynamic force, or CAZS delivered hydrodynamically. Results were assessed by counting colony-forming units (CFUs) and by confocal scanning laser microscopy (CSLM).

RESULTS: All treatments produced significant reductions in CFU counts (p >or= 0.002). Hydrodynamic CAZS provided the greatest reduction, decreasing CFU counts from control values by 3.9 +/- 0.3 logs and 5.2 +/- 0.5 logs for S. aureus and P. aeruginosa, respectively (99.9% reduction; p = 0.001). CSLM showed decreases in biofilm coverage.

CONCLUSION: Hydrodynamic delivery of a soap-like surfactant and a calcium-ion sequestering agent may disrupt biofilms associated with CRS. Our results may be relevant to a new approach to refractory CRS.
 

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