Sure, you can use a few drops of DMSO - just be careful to keep things clean and avoid contaminants like Zlatin said. DMSO is a very powerful penetrant that will take just about anything it comes into contact with into the skin. I found that out the hard way when I stored a topical solutions that had some DMSO in it (along with CS, oleander extract and iodine) in an inappropriate plastic container and ended up with plasticized fingernails for quite some time. I shudder to think of the plastic that went into my skin on my fingers and where I applied it.
Have you tried magnesium oil? Lots of great reports of using it topically for muscle problems. Plus, most of us are deficient in the vital mineral Magnesium.