But, the immune system is dependent on Vitamin D for its regulatory role and activation.....................
Vitamin D and immune function: understanding common pathways.
"Both the vitamin D receptor and CYP27B1 can be constitutive or induced by the ligands that activate the immune processes in these cells, providing feedback loops that help regulate the immune response. In general, 1,25(OH)(2)D(3) suppresses most elements of the adaptive immune system while inducing most elements of the innate immune system. Thus 1,25(OH)(2)D(3) may be protective against various autoimmune diseases and may limit graft rejection by suppressing adaptive immunity **(while enhancing the first line of defense against invading microorganisms via up-regulation of innate immunity)**."