I have heard that those two enzymes you listed are good for blood thinning, meaning, helping to prevent clots. However I then read recently that they can be dangerous, as they can break up every single clot in the body, even in areas where they shouldn't be broken up? Not sure what benefit there is to having any clots in the body, but I guess someone was saying certain parts of the brain have areas where you don't want the blood to be thin? I don't know, it's very confusing. My doc is suggesting I try the Nattokinase, but I am leary of trying it now.