South Carolina - Any Thoughts?

I have been to South Carolina several times and it is one of my favorite places to go. We usually go to the Charleston or Columbia areas.

I think I would like to take a few days off and go up around Greenville. I have never been to that region of the state.

Anyone have any suggestions of places to go or things to do around that area? I can only be there for 2 or 3 days - Saturday through Monday.