Well I have certainly felt that way at times all of my life. At one point when I was about 50 I thought "Tnis is the end, no hope for me." Then I read one of Dr Hulda Clark 's books, started doing what she advised and a year later was back at work. The main cause of the Depression in me was that I had toxin producing bacteria in my intestine. I did as much of her bowel program as I could with great success - Depression lifted and more energy. The problems would come back so I had to keep doing her procedures. Years later I found out I'm sensitive to gluten, a problem Clark didn't mention, and have found that I can use Clark's and other methods to cure these problems as long as I stay gluten free.