I had had a very bad case of poison ivy one year and I just so happened to be speaking to a neighbor of mine who recommended something called Ivyoff. He said it's the only thing that works. Since I was desperate, he gave me his last bottle. I have to say, I got relief in just a few minutes. Better than all the vinegar, bleach, dishwashing soap, baking soda, and toothpaste. I went and bought 3 bottles - one to replace my neighbor's, and 2 for me to keep. I highly recommend the Ivyoff as I've never had a bad breakout since that time. From time to time, yes, but I use the Ivyoff right away and haven't suffered since.