I took Diflucan for about a week. I noticed almost an immediate response. My stomach and gut felt like it was on fire, so I assume it was doing something. My bloating and stomach pains went away. Problem for me was I developed a persistent headache that would not go away. That was concerning. My doctor then prescribed nystatin. But, I don't think this is going to be as effective as the diflucan from what I've read, so I don't know what I'm going to do.