There is no way to use bloodroot on the skin "effectively" without some really bad scarring. And the problem often comes back if you don't take it orally and get it in your bloodstream. Therefore, why not just take it orally and avoid the scars? It is not easy to take, but it works, when nothing else will. If I had something on my skin that needed to come off, I'd go to a dermatologist, have him remove it with a nice neat scar, refuse radiation and chemo, and take bloodroot internally.