My daughter recently came down with PUPPP. She was only 12 weeks pregnant at the time (2nd pregnancy). From the research we found, PUPPP is usually cured by the delivery of the baby if contracted during pregnancy. Additionally, most PUPPP is contracted in the third trimester. Because my daughter developed this rash in her first trimester we did a lot of research in hopes of finding some relief. It would be a long and miserable pregnancy otherwise. I went to the health food store and bought a few items which my daughter said gave her the first relief, TEA TREE OIL LOTION & PINE TAR SOAP. Then we found a great nutitionist who researched PUPPP and recommended Probiotics and Omega 3. However, she found a cream made specifically made for PUPPP and it has worked on my daughter who is now 15 weeks pregnant. Here is the website: