The best dewormer is Barefoot's to get to the liver and colon. We don't think it is a good idea to go off the dewormer. "Resistence" is when we let them get back to their original numbers. Of course they do resist being killed and do hide. If we stop the dewormer, then in about 3 days the newly hatched eggs are ready to reproduce again. That's a good general rule. I didn't dare go off the dewormer till I saw no more parasites. 6 months prior to doing this program I killed off a few pinworms with some kind of brand name bug killer that wasn't worth much. The parasites came back. I only saw a few pinworms with that stuff. Then I dumped what parasites I had--about 7 quarts-- over a year or so while doing this program. Not to say you have that many. My experience says nobody knows but us people here what a problem parasites can be or how long it takes to get rid of them. Especially no doctor would dream it would take so long because they won't admit parasites have anything to do with cancer or other diseases. They've probably never heard. To them it's just that you may have parasites, so let's give you something for them for a couple of weeks and that should do it. WRONG! In most cases and certainly no drug can be taken long enought to get rid of them. They just come back. The eggs have to be killed and the junk off the colon walls whre the bugs hide their eggs, then the liver needs to be cleaned out in case any got in there. It's the solvents these days that we get on our skin or that we're exposed to that makes the eggs hatch in the intestines, because the stuff dissolves the covering on the eggs themselves. Years ago, before all the chemicals and solvents, the eggs just passed right thru. Doctor's drugs are the worst for predisposing our bodies to chemicals and parasites. So I wouldn't make a bet that most people I meet on the street don't have parasites. If they have any diseases, they have parasites.