pain in lower side with milk thistle

I just wanted to know if this was normal. about a month ago I took milk thistle because of it's cleansing affects on the liver. Instead I had a bad reaction, first I got really constipated, then my Acne flared really bad into cyst, my breast got so tender I could barely sleep or exercise, I got bad headaches, and irregular heartbeats, and I started to get a pain on the lower left side of my back, around my kidney area, had anyone had this? I've stopped taking it.