The Colosan stops working due to the fact that your body is some what magnesium deficient. Thus your body soaks up the magnesium oxides. To further have the colosan to work , you need to up your dosage to perhaps 2 tsps per usage or day now. I was up to 2tsp twice a day at one point. The rumbling is due to the fact it is working. Colosan is a primarily a small intestinal cleaner. Despite it says full intestinal cleaner. And yes enema's would work good, but a colonic wuold greatly benefit you the most. Colosan does work wonders i've been using it for jus over a month now and its remarkable whats coming out. Take care Jeff =)