When I have used Black Ointment to pull out cysts or abscesses, I have kept it on there continuously until I can pull it out. I put it on generously and then cover it with gauze. Then I change it twice per day, usually morning and night. The kind of Black Ointment that Christophers carry is not the same thing as the Black Salve that is used for cancer. Black salve has blood root in it which is used for drawing out cancer - the Black Ointment does not contain this particular ingredient.