Thank you for your response. I have started using it and consider it to be a godsend! My only regret is that the doctors and nurse practitioners didn't listen to me these past years and prescribed it back then. Right before I got prescribed it, I read that eating 2 teaspoons of flaked coconut a day helps with diarrhea. So I started adding it to my Activia and it made a big difference. The Cholestyramine was the icing on the cake. I haven't had to take Immodium in months (knock on wood!). It feels like I've gotten my life back.