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Image Embedded Nitazoxanide is an action-not a poison?
 
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Published: 17 y
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Nitazoxanide is an action-not a poison?


Nitazoxanide, which is a 5-nitrothiazole compound and a member of a new class of pyruvate:ferredoxin oxidoreductase (PFOR) inhibitors. Nitazoxanide has been shown to have activity against protozoa, "helminths" (lymes)) and bacteria in vitro, in animal models or both.

The antiprotozoal activity of nitazoxanide is believed to be due to interference with the pyruvate:ferredoxin oxidoreductase (PFOR) enzyme-dependent electron transfer reaction, which is essential to anaerobic energy metabolism. It is probable that nitazoxanide is selectively toxic for organisms capable of intracellular reduction of the nitazoxanide nitro group to a toxic free radical.

The bottom line is—Nitazoxanide mechanism of action "shuts down" cellular respiration of the target organism Sarcocystis neurona to kill the parasite.1

Life cycle chart......funny it has every animal but human.....are we to beleive we are different?


http://upload.wikimedia.org/wikipedia/commons/1/13/Equine_Protozoal_Myeloencephalitis_life_cycle.jpg


 

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