Re: Anthelmintic Study - Ficus Latex on Ascaris

Surprisingly, I came across the below while researching on something else. Unfortunately, it is an Abstract and not the entire article which needs to be purchased, but the Abstract is a good indication that latex is being looked into.


http://www.ingentaconnect.com/search/article?title=anthelmintic+resistance&

title_type=tka&year_from=1998&year_to=2008&database=1&pageSize=20&index=27


Human gastrointestinal nematode infections: are new control methods required?

Authors: Stepek, Gillian; Buttle, David J.1; Duce, Ian R.2; Behnke, Jerzy M.2

Source: International Journal of Experimental Pathology, Volume 87, Number 5, October 2006 , pp. 325-341(17)

Publisher: Blackwell Publishing
Abstract:
Summary

Gastrointestinal (GI) nematode infections affect 50% of the human population worldwide, and cause great morbidity as well as hundreds of thousands of deaths. Despite modern medical practices, the proportion of the population infected with GI nematodes is not falling. This is due to a number of factors, the most important being the lack of good healthcare, sanitation and health education in many developing countries. A relatively new problem is the development of resistance to the small number of drugs available to treat GI nematode infections. Here we review the most important parasitic GI nematodes and the methods available to control them. In addition, we discuss the current status of new anthelmintic treatments, particularly the plant cysteine proteinases from various sources of latex-bearing plants and fruits.

Keywords: anthelmintic; control; gastrointestinal nematodes; human; plant cysteine proteinases; resistance

Document Type: Research article

DOI: 10.1111/j.1365-2613.2006.00495.x

Affiliations: 1: Division of Genomic Medicine, University of Sheffield, Sheffield, UK 2: School of Biology, University of Nottingham, Nottingham, UK

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