Although, E. coli might be "resistant", much like MRSA has been reported, I believe there is answer in using herbs. Studies have found that MRSA was effectively killed by using something simple - the ancient herb garlic - it turned out to the be answer! Of course, big pharm wants their share of a "cure" so garlic is never an option.
I believe if you read some postings that I've done on E. coli you may find some answers somewhere. These are a good start to read on.