How much would you like to pay for your placebo?
I really believe that's why even people seeking "natural" healing
aids are drawn to the high priced snake oil sales pitches of many natural remedy
sellers, and that's why the simple things are no longer used. Like garlic,
flax seed, and pee.
It isn't the mind that heals, it is the human spirit. If the human
spirit believes it is healing, it is - regardless of what you do with your body
(even though you should listen to it).
Pricey pills work better even if they're
fake
$2.50 placebo eased more pains than identical 10-cent pill,
study found
By Roni Caryn Rabin
Special to MSNBC
updated 1:00 p.m. PT, Tues.,
March. 4, 2008
When it comes to painkillers, many people believe
“you get what you pay for,” according to a new study that found patients are
actually more likely to get relief if they think they’re taking high-priced
pain pills.
Volunteers who were given a placebo said to cost $2.50
per pill and described as a “potent opioid-agonist that provides fast-acting,
long lasting relief” were much more likely to report pain relief than
those given a placebo described as a discounted ten-cent version of the same
pill. The study is published as a research letter in this week's Journal of the
American Medical Association.
“Placebos work because people expect them to,” said
Dan Ariely, the corresponding author of the paper, a professor of behavioral
economics at the Massachusetts Institute of Technology in Cambridge and a
visiting professor at Duke University. “The interesting thing is that once you
have a discounted price, it basically cuts people’s expectations. They don’t
expect it to be as good, and then it might actually not be as good.”
The study, carried out in Boston, included 82 paid
volunteers. All of the volunteers were told about a new drug that had recently
been approved by the Food and Drug Administration, but half were told the drug
was regularly priced, while the other half were told it had been discounted.
The volunteers were then administered a series of mild
electrical shocks that were calibrated to their individual level of pain
tolerance. The shocks were administered before the volunteers took the pills and
again afterward, and the changes in the subjects’ responses were recorded.
‘Expectations are key’
Although the pills were actually placebos consisting of no more than vitamin C,
85 percent of the volunteers who thought they were taking the higher priced
painkillers experienced a reduction in pain, compared with only 61 percent of
those taking what they thought were discounted pills.
“Expectations are key,” when it comes to the
placebo effect, said Ariely, author of "Predictably Irrational:The Hidden
Forces That Shape Our Decisions."
The study underscores how powerful the placebo effect
is, but also helps explain why patients may be dissatisfied with cheaper generic
drugs, even though they are equivalent to the branded medications they replace,
said Dr. Adriane Fugh-Berman, an associate professor at Georgetown University
School of Medicine and the principal investigator of PharmedOut, a project that
educates physicians about the influence pharmaceutical companies have on
prescribing.
“Expectations are manipulated by manufacturers, and
drug companies are coming up with all kinds of strategies to convince consumers
that it’s worth it to pay more for higher priced drugs,” said Fugh-Berman.
“If you’re expecting a medication to work, or if your health care
practitioner increases that expectation in you, it may work better for you, at
least for symptoms like pain, which are very responsive to placebo.”
More than triple the cost
The average cost of a prescription for a brand medication is $111.02,
compared to $32.23 for a generic prescription, according to the National
Association of Chain Drug Stores.
The study also demonstrates that the placebo effect can
be modulated depending on how the placebo is presented, said Ted Kaptchuk, an
associate professor of medicine at Harvard Medical School, who has studied the
placebo effect.
“How you package the experience and how you dress it
up leads people to expect different outcomes, and those outcomes become embedded
in human biology,” Kaptchuk said. He added, “This is just more evidence that
the experience of illness is not only a biological event. Our beliefs, our
imagination, our expectations, the environmental cues we receive all contribute
to how we experience illness and health.”
Roni Caryn Rabin is a health writer who lives in
New York City. She has written for The New York Times, The Washington Post,
Newsday and Real Simple magazine, among other publications, and is author of the
book, "Six Parts Love: A Family's Battle with Lou Gehrig's Disease."
She teaches journalism at the Columbia University Graduate School of Journalism.
© 2008 MSNBC Interactive
URL: http://www.msnbc.msn.com/id/23455819/