I did. I started pulling about a month ago; a couple of days into I got five or six cankers all at once (and I'm not really prone to cankers so I figured it was a detox reaction). I vascillated about stopping the OP, but decided to suck it up. I bought some topical canker stuff to get me through the day; and I OP'd three times a day. They were all gone in two days (even when I do, infrequently get cankers, they've never gone away that fast!).