I wonder if doing an enema is safe with baking soda. I would imagine one would have to be very careful not to upset the electrolyte balance. An interesting concept. Enemas have been so effective so it is obvious that in my case anyway the affected areas are being reached by the enema. I would definately try driking it first and see what havoc that wreaks and then possibly try it in enema. it was mentioned in the OP link top use it in enema for colon issues. But how much is safe? I am going to see if I can find any info on that.