all i know is i have never had a history of migraines. i started getting migraines a year after i got mirena when my other side affects atarted. i have a history of constipation and now it is worse since mirena. i almost feel like my colon wants to stop working. before mirena i used to get a slight headache and diarrhea right before i started my period. i have a hard time losing weight with mirena.