Re: info on iodine loading test

available here:


http://www.breastcancerchoices.org/loading.html


and, an explanation, follow the link for more info:


http://www.vrp.com/articles.aspx?page=LIST&ProdID=1797&qid=&zTYPE=2


"Orthoiodosupplementation is the daily amount of essential element Iodine required for whole body sufficiency. Whole body sufficiency for Iodine is assessed by an iodine/iodide loading test.1-3 The iodine/iodide loading test is based on the concept that the normally functioning human body has a mechanism to retain ingested Iodine until whole body sufficiency for iodine is achieved. During orthoiodosupplementation, a negative feedback mechanism is triggered that progressively adjusts the excretion of iodine to balance the intake. As the body iodine content increases, the percent of the iodine load retained decreases with a concomitant increase in the amount of Iodide excreted in the 24 hour urine collection. When whole body sufficiency for iodine is achieved, the absorbed iodine/iodide is quantitatively excreted as Iodide in the urine. Whole body sufficiency for iodine is arbitrarily defined as 90 percent or more of the ingested iodine/iodide load (50 mg) recovered in the 24 hour urine collection.1

In some very rare cases of severe iodine cellular transport defect/damage, the absorbed iodine/iodide is quantitatively excreted in the urine, even though the target organs are very iodine deficient. We have reported only three cases over the last three years.3,4 One case was studied in detail using post-iodine load serial serum Iodide levels before and after supplementation with Vitamin C.4 The milder cases of iodide cellular uptake defect/damage are more difficult to detect. We are currently investigating the saliva iodide/serum iodide ratio as a means of assessing iodide cellular transport effectiveness."