I take mine around 11 am, and I usually always have had something to eat first, something small to go with the 1 cup of coffee I might drink & 1 pc. of 12 grain toast. I eat around 10 am. I put my Iodine in a cup of water and drink it, then take my companion supplements, except for V-C which I have later thru-out the day since I'm taking mega doses right now of it.
My son likes his with orange juice and he usually has eaten also, but he's nocturnal..so it's hard for me to say..he was taking his in the evening. He since has moved out to find his destiny. He abscounded with the Iodine too! Although he did leave me some of it. He left abruptly with no warning to me of his impending leaving! I give that to Iodine, that which I could not do:)