Sorry pb3046. I did not mean to imply that such dosage was dangerous. I mean that I would not be brave enough to try. I have only gone to 20 drops; and did not stay there long. I'm pretty sure my detox symptoms would overwhelm me higher than that. Just as too much vitamin C would keep me on the toilet all day. I just wonder how others can get away with it and I can't. I must be filthy inside.