Some Dentists are filling root canals Calcium Oxide. Also, many times if you have a failed root canal, this substance will be suggested. Calcium Hydroxide is formed in root canals that are filled with Calcium Oxide. When I read the MSDS on it a few years ago, I decided it was a caustic poison that I would not want in my jaw. Doctors such as Hal Huggins, George Meinig, and other Biologic Dentists, agree. Composition and toxicity: