Myasthenia Gravis (MG)
Myasthenia gravis (MG) is the most common primary disorder of neuromuscular transmission.
What was once a relatively obscure condition of interest primarily to neurologists is now the best characterized and understood autoimmune disease.

EPIDEMIOLOGY
Approximately 36,000 cases in the United States. Myasthenia gravis is probably under diagnosed.
Previous studies showed that women are more often affected than men.
As the population ages, the average age at onset has increased correspondingly, and now males are more often affected than females, and the onset of symptoms is usually after age 50. Patients with myasthenia gravis come to the physician complaining of specific muscle weakness and not of generalized fatigue. Ocular motor disturbances, ptosis or diplopia, are the initial symptom of myasthenia gravis in two-thirds of patients; almost all had both symptoms within 2 years.



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