when I was getting treatment for parasites drugs were rotated and life cycle of parasites was taken into consideration as some of the meds only worked for a certain stage of parasite as well as some were all body meds while others were only gut intestinal tract meds. Never used the product DE but did use other holistic products during off days of meds. They do develop resistance - I have read how pigs and other farm animals develop drug resistance or the parasites within them develop resistance to certain meds- its a huge industry keeping the herds clean - my cousin actually develops pharma meds for animals just for this purpose

I took DE for about 45 days, 1-4 tbsp twice a day.

Didn't do daily enema and regular Liver Flush as wasn't aware about doing these during parasite cleanse process, though should have done these. Though one must be careful before starting Liver Flush as Liver Flush without parasite cleanse could scatter worms in body.

DE only works in intestine but parasites could be all over the body (brain etc.)

The advantage of DE is it acts mechanically.

I no longer use DE and went back to the usual Black-Walnut , Wormwood , clove etc. protocol.

DE is loaded with silicon which your body uses to manufacture nails, hair etc.

I have never read any finished studies using DE and think it is a little overhyped.

The other poster makes a valuable point in that resistance is a growing problem which has to be addressed.

The first step is to determine which substance provides sensitivity, that means substance A may kill off one type 1 or an organism while it has no effect against type 2.

Resistance is shown at days 4-7 of the treatment and it is recognized as when the organism will rapidly die off - if the organism is resistant then after day 7 it will show itself again. Most organisms are able to resist via the efflux pump mechanism and by stopping the pumps then the substances are able to retain inside the cell where they do their work.

Herbs tend to be the best remedy for the resistance and many of them will stop resistance. The best I know of is Goldenseal Leaf (not GS root). The leaf contains many constituents that stop the efflux pumps from working. There are many other herbs that can do this and if anyone is interested then send me a PM.

Studies show that combining these herbs along with drugs offers a better chance for the drugs to work.