There a several reasons for lyme disease treatment failure. Antibiotic resistance and molecular penetration are very important. Your bones get infected and you need to treat those too.

So when the bone is itself, say the jawbone for example, is infected that is called, "Osteomyelitis"

Osteomyelitis is Bartonella's forte so not only does it add the transgenic capacity to create fibers from your skin proteins , it also infects your bones.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC165354/

"Osteomyelitis Caused by Bartonella henselae Genotype I in an Immunocompetent Adult Woman"

http://jmm.sgmjournals.org/content/57/4/519.full

"Abscess-forming lymphadenopathy and osteomyelitis in children with Bartonella henselae infection"

http://cid.oxfordjournals.org/content/35/12/e141.full

"Vertebral Osteomyelitis Due to Bartonella henselae in Adults: A Report of 2 Cases"

There are a lot of these studies available.

The bone is very dense, it is made of a collagen fibril matrix reinforced with minerals, it's hard to penetrate. You need molecules that are small enough to do that. In pharmacology they use a 500 dalton rule of thumb for tissue penetration, but that's too big to get into the bones. So you need a treatment with small enough molecules to clear the bones and you need to do it consistently for long enough duration to accomplish that.

http://www.ncbi.nlm.nih.gov/pubmed/10839713

.

"The 500 Dalton rule for the skin penetration of chemical compounds and drugs."

It's easy to look up the molecule size of an antibiotic.

Mycobutin for example is 847.005 g/mol , a mol is a molar mass and a dalton is wieght but they are roughly 1 dalton equals 1 molar mass.

http://en.wikipedia.org/wiki/Rifabutin

See the molar mass under "chemical data"

Everyone remembers putting bactine on a cut and then it stings. When I treated m own Lyme/Bart I could feel the treatment workin because it was just like that sting on a cut only inside my bones, I could feel it working in my bones.

Antibiotic molecules are not only too big they're just not that effective anymore;

http://www.sciencedaily.com/releases/2011/04/110411163918.htm

" Antibiotic resistance spreads rapidly between bacteria"


this is the method i used to cure myself, a no sales information only website;

http://www.lyme-morgellons.com