Tri-Boron, 3 mg, 100 Capsules
http://www.iherb.com/Twinlab-Tri-Boron-3-mg-100-Capsules/2446?at=0
More about Boron by Newport contact Newport 7/4/2007 2:25:52 PM ( 4 year ago ) Hits: 2644 Size: 12619 char. URL: http://www.curezone.com/forums/fm.asp?i=912424 Replies: 12 Status: RRR [Message recommended by a moderator!] Edit Disallowed |
Prior to 1981, boron was thought to be all but irrelevant in daily human nutrition. Since then, there have been a number of animal and human studies (including one by the U.S. Department of Agriculture) determining boron as essential for the hormonal influence of estrogen and testosterone as well as bone metabolism. It is also purported to have anti-carcinogenic potential as well as preserving cognitive function. From a scientific perspective, boron appears to have earned its place on our list of vital nutrients in the orchestration of health. It has, however, yet to receive any official recognition as an essential mineral – yet.
Anti-Cancer Activity of Boron. Studies of the anti-cancer efficacy of boron against a wide range of tumor cell lines (shown above) may warrant clinical trials in humans. BORON'S EFFECT ON BONE METABOLISM Calcium-Magnesium <=> Boron Interactions Large numbers of human experiments show that boron is vitally involved in bone metabolism. It is well accepted that calcium and magnesium are important constituents of healthy bone, and in situations of adequate calcium supply but deficient magnesium resources, boron appears to substitute for magnesium during the process of bone formation. Under such conditions, the concentration of boron within bone tissue increases. Boron's effect on bone appears to be mediated by its ability to reduce the urinary excretion of calcium and magnesium, and this ability is due to its actions in the kidney. As stated above, this calcium-preserving effect of boron becomes pronounced in circumstances in which dietary magnesium is low. Therefore, boron is in effect acting as a backup system for magnesium in order to preserve calcium in the blood and reduce urinary calcium loss. The effect of boron intake was analyzed in a human study involving 12 post-menopausal women not on estrogen replacement therapy. Patients were first given a boron-deficient diet consisting of 0.25 mg of boron daily for 119 days. This was followed by a 48-day period in which the same patients received boron supplementation at a dose of 3 mg per day. Patients were also studied during periods of adequate magnesium intake versus magnesium deficiency. Deprivation of boron and/or magnesium caused changes that are similar to those seen in women with post-menopausal osteoporosis, including increased loss of urinary calcium. However, in women receiving 3 mg of boron per day, urinary losses of both calcium and magnesium were significantly diminished, especially if dietary magnesium was low. Also noted were increased levels of plasma ionized calcium, beta estradiol, and testosterone. Boron also appears to enhance vitamin D, and although there is likely a relationship between this and it’s calcium-preserving effect, an accurate description for the mechanism of action of boron’s vitamin D enhancement is unclear. ANTI-INFLAMMATORY IMPLICATIONS Boron’s aforementioned theorized capability to inhibit carcinogenic enzymes led researchers to believe that it may also inhibit other harmful enzymatic activity as well. Boron has been shown to inhibit cyclooxygenase (COX) and lipoxygenase (LOX), two enzymes that mediate the inflammatory cascade and are pertinent to therapies directed against inflammatory conditions. Such anti-inflammatory capabilities of boron are clearly pertinent to its anti-cancer effect, because the reduction of COX II and LOX enzymes lead to a decrease in prostaglandin E2 (PGE2) and other unfavorable eicosanoids such as leukotrienes. We now know that omega-6 fatty acid metabolism that is allowed to continue down this pathway represents a vital stimulus for angiogenesis and cancer growth. We also now know that there are many parallels between the medical applications of non-steroidal anti-inflammatory drugs (NSAIDs) and the biological properties of boron. ARTHRITIS Prostaglandins and leukotrienes are mediators of inflammatory conditions such as degenerative joint disease and osteoarthritis. PGE2 and leukotrienes have been implicated in causing problems with joint swelling, restricted joint motion, and other arthritic complaints. There is evidence that boron may inhibit COX II and PGE2 by suppressing nuclear factor kappa beta (NfkappaB)—a proinflammatory cytokine. There is also evidence along these lines that boron can relieve arthritic conditions, which are essentially conditions of inflammation. These findings are clinically supported by evidence showing that areas of the world with low levels of boron in the soil have a higher percentage of people suffering from arthritis in comparison to regions with higher soil levels of boron. In fact, epidemiologic evidence shows that in areas of the world where boron intake is 1 mg or less per day, the estimated incidence of arthritis ranges from 20%-70%, whereas in areas of the world where boron intake is usually 3-10 mg, the estimated incidence of arthritis ranges from 0-10%. In a study of 20 patients with osteoarthritis, the 50% who received a daily supplement of 6 mg of boron all reported improvement (less pain on movement), compared to only 10% who reported likewise in the control group. In another study, it was revealed that bones adjacent to joints with osteoarthritis tend to be less mineralized and have significantly lower concentrations of boron. COGNITIVE FUNCTION It is now commonly accepted that the routine use of NSAIDs significantly reduces the incidence of Alzheimer's disease. Given their aforementioned similarities, it stands to reason that boron may also have a positive effect on cognitive function. Studies were conducted involving the analysis of brain wave patterns using an electroencephalogram (EEG) based on tests designed to measure cognition and motor skills in human subjects who were given diets that were either boron-rich (approximately 3.25 mg boron/2000 kcal/day) or boron-deficient (approximately 0.25 mg boron/2000 kcal/day). The EEG and showed an increased proportion of low-frequency activity in those subjects on the boron-deprived diet. The authors of these studies concluded that boron appears to play a significant role in human brain function and cognitive performance, and that it is an essential nutrient. BORON TOXICITY Doses up to 18 mg of boron daily appear to be safe for adults even if taken for prolonged periods of time. This is double the dose of even the most liberal amounts suggested by advocates of boron use. There is also no evidence to suggest that boron is either carcinogenic or mutagenic. In 1904, human volunteers consuming greater than 500 mg of boric acid daily (this is equivalent to about 180 mg of elemental boron) showed symptoms of poor appetite and digestive problems. Symptoms of acute toxicity typically include nausea, diarrhea and abdominal cramps. In Conclusion Although Boron has yet to receive official entry into the ranks of the much maligned yet all-powerful RDA charts, there is strong evidence to suggest that it soon will. Along with a number of other minerals, boron may soon be recognized as essential since it has undergone publicly-funded studies recognized by government agencies, some of whom are under increasing pressure to expand the list of minerals officially listed in the RDA charts. |
Doses up to 18 mg of boron daily appear to be safe for adults even if taken for prolonged periods of time. This is double the dose of even the most liberal amounts suggested by advocates of boron use. There is also no evidence to suggest that boron is either carcinogenic or mutagenic.
In 1904, human volunteers consuming greater than 500 mg of boric acid daily (this is equivalent to about 180 mg of elemental boron) showed symptoms of poor appetite and digestive problems. Symptoms of acute toxicity typically include nausea, diarrhea and abdominal cramps.
---------
Borax is nearly all Boric Acid, assuming you have USP or Pharma grade this says that 50 mg of Borax gives you 18 mg of elemental Boron the recommended high end dose.
I have a scale that weighs down to a gram, but no finer. I weighed 4 tablespoons of grocery-store borax, and got 38 grams. Going from that, a level tablespoon would weigh about 9500 mg, a level teaspoon would weigh about 3167 mg, a level one-quarter teaspoon would weigh about 792 mg, and a level one-eighth teaspoon would weigh about 396 mg. We can't recommend ingesting grocery-store borax, because sometimes people can respond negatively to the impurities present.
I've been taking borax for about 5 years similar to Ginagirl. I started using it, together with high dose lugols iodine, amongst other things, to get rid of my systemic candida problem(successfully gone now). I took the borax as borax water -- 1/8-1/4 tspn borax(sodium tetraborate) dissolved in one litre of water. Then I would add my daily dose of high dose lugol's drops into the borax water and drink that liter throughout the day. Works well, spreads the dosages safely throughout the day and I would always take a rest from the borax/iodine water at the weekends..
As far as I'm concerned, borax is the ultimate fungal killer and iodine's not so bad in that area either. I also spray the outside of my body after showering with a garden sprayer containing a mixture of epsom salts and borax in water -- keeps all the fungal skin problems in check and also removes and improves body odour. I have alot of respect for borax -- it balances hormones, removes fluoride from the body and is particularly good for increasing bone density. Borax is a life saver for people with arthritis because it kills the mycoplasma cause, a sort fungal Ebola-type of bacteria that eats and destroys cartledge. Anyway, here is some older research on borax and arthritis:
http://www.rexnewnhamarthritiseducation.com/paper.asp
In Israel their drinking water has a higher borax content than normal. The incidence of occurrence of arthritis in America is about 22% of her population across the board. In Israel, only 0.35% of their population has arthritis. Borax in action.
I still take iodine and borax today, though not as intensely as when I had the candida.
Other stuff I discovered in those early days was that everyone is deficient of minerals like Magnesium, Iodine, Borax and Vitamiin C etc. And there is way too much fortified Calcium in processed foods which acidifies your cells. It's interesting that when Dr Abraham -- from the Iodine Project -- did an experiment and tested 500 American people randomly with his iodine loading test he found that 97% of them were seriously iodine deficient. Additionally, because of bad processed foods, drugs, toxins etc that we constantly eat and drink, other antioxdants like Glutathione and SOD -- essential and protective body antioxidants -- are also sadly lacking in our bodies which is why I think our bodies age or "rot" so quickly. Part of the cause of this problem is the ridiculously low redommended RDA doses given for these nutient substances by agencies like the FDA.
I also had heart arrythmia and serious insomnia problems as well as bad leg cramps at night. Magnesium Chloride(Mag Oil) and Iodine -- in higher doses -- got rid of all those problems very quickly.
I always take minerals and vitamins now in my own larger amounts which has done me well. I've found it easiest to take mineral water of my own making -- consisting of borax, sodium bicarbonate(alkalizing), magnesium sulphate or chloride, lugol's iodine and fulvic acid drops(minerals baseline) in my drinking water. This, I think, gives me more or less the full spectrum of minerals that I need every day in an easier and more natural form to take than tablets and also seems to provide strong, protective antiobiotic action.
I also take 8 - 10 drops of 10% Sodium Thiosulfate in a glass of water a few times a week which continually detoxes and clears my system of heavy metals, chlorine, arsenic and cyanide. The iodine also helps to clear out lead, mercury, aluminium and cadmium as well. You can by 10% ST from any aquatics shop -- used for removing chlorine from fishtanks. They also use Sodium Thiosulfate -- in much larger amounts -- in medicine as an IV flush after you've had chemo for cancer to help clear out the heavy metals. I just use !0% ST as a gentle, constant detox, as a defence against any processed food I might eat. No side-effects at all. Eating raw cilantro in salads and drinking green tea will also help detox heavy metals from the body.