In recent weeks there has been a lot of misinformation and disinformation posted about medicinal oleander - including that it is highly toxic, that it is a bogus remedy and that there is no proof of effectiveness. I won't speculate about the motivations for posting such bogus misinformation here, but I will take this opportunity to set the record straight.
First of all, I absolutely acknowledge that oleander is a very toxic plant in raw form and I will also acknowledge that I may have been remiss in not posting a warning about raw oleander's toxicity in every single post I have made about oleander. However, I believed that it was obvious that I was discussing medicinal oleander and not raw oleander. Medicinal oleander - whether in commercial supplements or in the homemade "oleander soup" version - which have been discussed at CureZone as possible solutions for cancer, HIV/AIDS, hep-C and so forth, is NOT highly toxic. Neither is it a bogus remedy and neither has there been no proof of effectiveness.
REGARDING THE SAFETY OF OLEANDER
As best I can tell, my first post at CureZone came on May 24, 2007. When I began posting about oleander, I made it quite clear from the very beginning that raw oleander was toxic and should not be fooled around with, as is demonstrated in the message I posted July 1, 2007 explaining how to safely make the homemade extract:
http://curezone.com/forums/fm.asp?i=910445
http://curezone.com/forums/fm.asp?i=911320
At the very beginning of the instructions for making the homemade extract there are these warning paragraphs highlited in red:
Please note: Raw oleander plant is extremely toxic. Do not handle or ingest raw oleander or any form of oleander that has not been prepared according to the recipe for “oleander soup” in this book or the commercial products whose links are provided on the last page of this book. While raw oleander is toxic, there have been no reports of serious adverse reactions or side-effects due to properly prepared oleander extract taken according to directions. The most common side-effects are loose bowels, slight temperature and perhaps mild nausea, all of which should dissipate quickly as the body becomes acclimated to the extract.
This information is furnished for informational purposes only and nothing contained herein is intended to diagnose or treat any medical condition. Anyone with a medical condition or seeking medical advice is urged to seek out a qualified medical professional – preferably one well versed in integrative and/or naturopathic medicine.
The homemade extract as well as the commercial supplements discussed at CureZone have all been based on the extract which has been used safely and successfully in thousands of cancer patients for over 40 years by Dr. H. Z. Ozel in Turkey. His extract was ultimately patented and put into an FDA phase I toxicity trial. As the trial stated:
"Traditional dose limiting toxicity was not seen, but the MTD was defined by injection volume as 0.8 ml/m2/day."
In other words, the trial never did reach an unsafe toxic level, but rather reached a level where it was impractical to inject more oleander.
http://www.ncbi.nlm.nih.gov/pubmed/16763787
Those who would like to detract from oleander point out that no tumor responses were noted in the trial. However, what they fail to point out is that the trial only lasted for 3 weeks for most participants and its only purpose was to determine toxicity. Oleander does not usually work overnight when it comes to cancer, but rather usually works slowly but surely where it first begins to slow tumor growth (normally within the first two months), then stabilizes tumor growth and then ultimately regresses tumors until they often are no longer present at all.
REGARDING THE EFFECTIVENESS OF OLEANDER
It has been posted elsewhere that there is no proof of oleander's effectiveness in humans, that only limited petri dish studies have been conducted, that no further human trials have been conducted and even that one trial has been unable to recruit enough participants to be conducted - all of which are blatantly false. The truth is that oleander's effectiveness has been abundantly proven both scientifically and in real life experiences and that another trial of an oleander extract has been successfully conducted and concluded and is in the final write-up stages for presentation to the FDA. That trial was the very same one which another poster alleged had been unable to recruit enough participates, which the poster would have found out if they had done a better job of researching.
Though the most recent trail was also an FDA phase I trial intended to primarily identify limiting toxic doses, it was a somewhat longer trial and did return some very positive results. At the end of two months, the cancers in 9 out of 20 enrolled patients had been stabilized and three of them had already begun to see tumor regression. Notably, the trial participants were not encouraged to make dietary and lifestyle changes or to include other immune-boosting and anti-cancer supplementations as is usually the case when someone incorporates oleander in part of an overall protocol such as the one I recommend. Thus the results seen can almost surely be attributed to oleander alone. As soon as I find that the FDA write-up has been completed I will be reporting on it.
In real life, the aforementioned Dr. Ozel has a multitude of case reports which vouch for the effectiveness of oleander. Some of those are:
Mesothelioma - HD
http://www.drozel.org/eng/diagnosis_mesothelioma_HD.htm
Adenocarcinoma (epithelial type malignant mesothelioma?) - US
http://www.drozel.org/eng/diagnosis_adenocarcinoma_US.htm
Small cell anaplastic carcinoma in the lung -YG
http://www.drozel.org/eng/diagnosis_smallcell_YG.htm
Malignant lymphoma, lung cancer - MG
http://www.drozel.org/eng/diagnosis_malignant_MG.htm
Prostate cancer with bone metastases - KE
http://www.drozel.org/eng/diagnosis_pancreas_SO.htm
Pancreas cancer with bone metastases - SO
http://www.drozel.org/eng/diagnosis_pancreas_SO.htm
Pancreas cancer - MH
http://www.drozel.org/eng/diagnosis_pancreas_MH.htm
Peritoneal carcinosis - HA
http://www.drozel.org/eng/diagnosis_peritoneal_HA.htm
Inoperable stomach carcinoma with metastases -VO
http://www.drozel.org/eng/diagnosis_stomach_VO.htm
Brain tumor - AS
http://www.drozel.org/eng/diagnosis_brain_AS.htm
Brain tumor - SD
http://www.drozel.org/eng/diagnosis_brain_SD.htm
Breast cancer (Ductal carcinoma) - SE
http://www.drozel.org/eng/diagnosis_breast_SE.htm
Antrum cancer - YT
http://www.drozel.org/eng/diagnosis_antrum_YT.htm
Brain tumor - EO
http://drozel.org/eng/diagnosis_brain_EO.html
There are also many other case reports about the successful use of oleander, as researched and reported in the book I wrote.
Then there is the 100% successful double-blind placebo controlled study on actual humans which was conducted at a Johannesburg, South Africa AIDS clinic:
http://www.tbyil.com/HIV_Clinical_Trial.htm
http://www.tbyil.com/HIV_OPC_Trial.pdf
And finally there are the abundant real life success reports and unsolicited testimonials from actual humans about the success they have had as a result of taking supplemental oleander (and other recommende items) including a number of individual reports posted here at CureZone and this compilation:
http://curezone.com/forums/fm.asp?i=1661043#i
No one is suggesting that oleander is a miracle cure-all or that it is right for everyone or best for everyone. However it is quite obvious that, despite the misinformation and disinformation that has been posted elsewhere, the real truth is that oleander has been very successful in actual human use in many, many instances - especially when combined with an over all anti-cancer lifestyle and protocol.
I note that the primary source of contrary information about oleander has posted a rebuttal in his own forum.
In the post, he once again disputes the actual facts, accuses me of lying and attempts to belittle me and what I have posted. It is the same style of posting which has resulted in him being banned in several forums across CureZone (at least eight as best I can figure) and having a great many posts removed across CZ, including those in his own forum.
So, according to this other poster, 40 years of successful use by a noted doctor in Turkey do not count, actual medical case reports do not count, real life unsolicited success stories and testimonials do not count, and an actual FDA trial on humans does not count (or is conveniently ignored and misreported). All that counts is the poster's opinion and more of the same misinformation.
One example: the false claim is made that says that a trial was unable to recruit enough participants. The source of this claim is an NIH listing for the trial which has never been updated to show the actual status of the trial - and the poster jumped on this as proof that the trial could not find enough "guinea pigs" to even conduct the trial.
Should the poster, who claims to have superior research skills, have checked further before leaping to conclusions, he would have found that in actuality there was no problem in recruiting participants and many were turned down. In actuality, the trial was conducted and has now been concluded - and the results are in the final write-up stage for presentation to the FDA. In actuality, the trial was quite successful and, though designed primarily to determine toxicity, the trial produced notable success against cancer in many participants.
One could have easily verified the truth about the trial by contacting the people who sponsored and ran the trial. But then, the poster was well aware of the inconvenient truth about the actual status of the trial because I had pointed it out to him before.
In actuality, the testimonials referred to have come from actual human beings. I know this because many of them were posted on the Yahoo group I host by the group members. I also know this because I have seen copies of emails and letters to the person who formulated herbal supplements based on the patented medicine extract which has been used for over 40 years.
Trying to dismiss the testimonials as bogus and label those who have reported them - including myself and the person who formulated the herbal supplements - as liars is typical of the other poster's tactics and it is also typically false. Likewise it is typically false to label my informational website which supports itself with advertising the same as does CureZone, as a sales site.
I find it more than a little ironic to see such a claim from someone who apparently conducts a thriving business of selling his own herbal products from his private forum. Likewise I find it more than a little hypocritical to keep harping on about posts about "oleander soup" which did not contain a warning in every instance when the record will clearly show that such warnings were not made in every single post he has made about a favorite of his - ozone, which is a known toxin for humans and which runs the risk of ozone poisoning when not used properly. And the other poster complains about double standards?
In conclusion: in actuality, oleander extract has been shown to be successful in actual humans in actual medical use, in use via supplementation AND in actual human trials. That is the actual truth, regardless of what disinformation is posted to the contrary.
Once the final write-ups for the recently concluded FDA phase I trial have been completed, I will report on them. I suppose that they too will be labeled as bogus.
That's what I thought when I wrote that article.
: )