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Reducing Anger and Depression with Zinc Intake.
Depression has been classified as a mood disorder or affective disorder. Mood is defined as a pervasive and sustained emotion that, in the extreme, markedly affects a person's perception of the world and ability to adequately function in society. Mood disorders are among the most common encountered in clinical practice and are divided into depressive disorders and bipolar disorders. Depression is a common disorder that affects approximately 5 percent of the population at any given time, and about 30 percent of adults will suffer from depression over a lifetime. Commonly thought of as a disorder of young to middle adulthood, with an average age of onset in the late 20's, depression is also recognized as a common psychiatric illness in the elderly. Women are two to three times more likely to suffer from depression than men. Zinc is necessary for the functioning of over 300 different enzymes and, as such, it plays a vital role in an enormous number of biological processes. Zinc is widely distributed in microorganisms, plants, and animals. In humans, the highest concentrations of zinc are found in the liver, pancreas, kidneys, bone, and muscles. Zinc is highly concentrated in parts of the eye, prostate gland, sperm, skin, hair, and nails. Cooking acidic foods in galvanized cookware used to be a possible source of excess zinc intake. The widespread use of stainless steel and plastic materials to prepare and store foods has largely eliminated this problem. A recent study published in the European Journal of Clinical Nutrition investigated whether zinc supplementation could improve mood disorders. This double-blind, randomized, placebo-controlled trial involved 30 women who were placed into two equal groups. They were given either a multivitamin (MV) or a MV and 7 mg zinc every day for 10 weeks. The results were the women who took MV and zinc showed a significant reduction in anger and depression and a significant increase in blood levels of zinc in comparison to the women who only took the MV. The researchers concluded by stating that their results suggested zinc supplementation could be used to reduce anger and depression. 1Sawada T, Yokoi K. Effect of zinc supplementation on mood states in young women: a pilot study. Eur J Clin Nutr. Mar2010;64(3):331-3.
Before that I also tried tyrosine and gaba but that did not do anything for me. Tried it for several months.
These are best taken separately. One is building neurotransmitters and the other is inhibiting the neurotransmitters.
I've read that zinc supplementation reduces copper levels. Should supplementation with zinc and copper be a 10 to 1 relationship?
Yes, high levels of zinc will displace copper. This is why some supplements contain 50mg zinc with 2.5mg copper.
I think there is a lot in this idea, certainly worth a bit of extra study, considering the amount of clinical depression diagnosed today.
On a side note, I have also found tyrosine to be very helpful in reducing depression and anger.
Yes, tyrosine can help with some cases of depression due to its effects on the thyroid and by acting as a precursor for dopamine and norepinephrine, which all can cause depression if low.
On the other hand it will not work in all cases since there are so many causes of depression other than low dopamine, low norepinephrine and low thyroid. I can also be low serotonin, low adrenal function, low prostaglandin levels, high prolactin levels, nutritional deficiencies, many medications can cause depression, etc.