Is there any possibility TMG can cause over methylation?
I have never heard of this occurring so I looked in to it and the whole thing seems to be in debate. All the sites saying yes just repeat each other word for word without any explanation. I found several sites that said no and they went in to a little more explanation. In short they say SAMe is a problem but not TMG due to the differences in the way they are metabolized.
and if so what would the symptoms be.
Symptoms of hyper and hypomethylation.
http://docs.google.com/gview?a=v&q=cache:u_HeYaqE_QUJ:www.johnshirley.net...
Hv I am taking 750 mg three times a day with meals as per your advice.Should I be concerned about it?
No, it is a very safe supplement, and the best sources I could find say that it is not a problem for overmethylation due to the way it is metabolized.