And a good natural remedy is....?
http://www.ncbi.nlm.nih.gov/pubmed/17116667?ordinalpos=4&itool=EntrezSyst...
The extracts and pure major constituents of Chios mastic gum (resin of Pistacia lentiscus var. chia) were tested for their activities against Helicobacter pylori. A total mastic extract without polymer (TMEWP) was prepared after removal of the contained insoluble polymer in order to ameliorate solubility and enhance in vivo activity. Administration of TMEWP to H. pylori SS1-infected mice over the period of 3 months with an average dose of 0.75 mg/day led to an approximately 30-fold reduction in the H. pylori colonization (1.5 log CFU/g of tissue). However, no attenuation in the H. pylori-associated chronic inflammatory infiltration and the activity of chronic gastritis was observed. To further characterize potential active mastic constituents, the TMEWP was separated into an acidic and a neutral fraction. Both were extensively characterized by nuclear magnetic resonance and mass spectroscopy to elucidate the structure of the components contained within each fraction. After chromatographic separation, the acid fraction gave the major triterpenic acids, while the neutral fraction gave several triterpenic alcohols and aldehydes. Mastic extracts and isolated pure triterpenic acids were tested for in vitro activity against a panel of 11 H. pylori clinical strains. The acid fraction was found to be the most active extract (minimum bactericidal concentration [MBC], 0.139 mg/ml), and the most active pure compound was isomasticadienolic acid (MBC, 0.202 mg/ml [0.443 mM]). Our results show that administration of TMEWP may be effective in reducing H. pylori colonization and that the major triterpenic acids in the acid extract may be responsible for such an activity. http://www.ncbi.nlm.nih.gov/pubmed/11806621?ordinalpos=1&itool=EntrezSyst...
In this study we evaluated the antibacterial activity of mastic gum, a resin obtained from the Pistacia lentiscus tree, against clinical isolates of Helicobacter pylori. The minimal bactericidal concentrations (MBCs) were obtained by a microdilution assay. Mastic gum killed 50% of the strains tested at a concentration of 125 microg/ml and 90% at a concentration of 500 microg/ml. The influence of sub-MBCs of mastic gum on the morphologies of H. pylori was evaluated by transmission electron microscopy. The lentiscus resin induced blebbing, morphological abnormalities and cellular fragmentation in H. pylori cells.In vitro and in vivo activities of Chios mastic gum extracts and constituents against Helicobacter pylori.
Bactericidal activity of Pistacia lentiscus mastic gum against Helicobacter pylori.
INTERESTING !!!
What are the chances that a duodenal ulcer diagnosed over 30 years ago and treated with only Tagamet could have left this bacteria to slowly wreak the kind of havoc I have experienced as a nightmare of symptomology over the last several years?
If you can rule out other possible causes such as the use of nonsteroidal anti-inflammatory drugs (NSAIDs) as the cause of the ulcer then I would say pretty good.
Have you had any tests to confirm H. pylori infection?
living in US know but, I am originally from the Aegean region where mastic gum trees grow naturally. we used to chew it like a gum. it is even stickier than a gum. So it sounds weird to see it in a pill. do they dry it and ground to encapsulate? even then, after capsule dissolves wouldn't the dried gum get sticky with gastric juicies and stick somewhere in the digestive track?
Yes, the resin is dried and ground. During the encapsulation they will add flow agents to make encapsulation easier. These flow agents will also help prevent clumping of the resin in the stomach. Same reason I have people mix non-resinous herbs with resinous herbs before ingesting the resinous herb. For example chaparral is quite resinous and will clump in to a "gum ball" when combined with moisture. Combining the chaparral with another herb such as pau d' arco helps to separate the chaparral particles reducing clumping. IN capsules silica powder is often used, and this can also serve this same purpose.
Hi, Do you know if H. Pylori and acid reflux can be associated with difficulty breathing? My doctor did an H. Pylori test and determined that I am infected so he put me on a treatment of antibiotics to no avail. I have tremendous trouble breathing and have been on inhalers and anxiety medication but I'm still not sure what's causing it. I've read tons of websites (cnn articles, h pylori treatment, Wikipedia, etc.) but I can't find it ever having been linked to H. Pylori? Could it be something else? This is really bothering me lately and my doctor can't figure it out. I am constantly light headed and can't think or even get anything done. Thanks, Sherri