As a 15 year prostate cancer survivor (still have my prostate) I ran across Essiac a couple of years ago and took it for a few months and didn't experience any detox reactions per se.  Don't know what you're looking for in the way of detox, but there were no symptoms of any kind, except for what I note a little later.  I get more detox symptoms from eating raw garlic than from Essiac.  (Raw garlic clears out parasites and heavy metals.)  The first time I ever ingested Essiac, I did experience a dizziness that lasted for several minutes - I could feel it go through my entire body.  That happened only for the first three or four days and has never happened since that first ingestion.  I began Essiac again around the first of December because of an increase in my PSA count with no side effects, then MMS around the 10th of December, with noticeable side effects.  Are the MMS side effects detox?  I wouldn't bet on it.  I'm still taking Essiac and MMS on a daily basis.