Blog: stem cell alternative cancer therapy
by jenny3289

stem cell therapy for parkinson's disease

Stem Cell Alternative Stem Cell Therapy

Date:   2/7/2006 9:21:33 AM   ( 16 y ) ... viewed 2533 times

Parkinson's Disease

Transplantation of stem cells directly into the brains of Parkinson's disease patients has shown great results. One man's own stem cells were extracted from his brain and subsequently transplanted into the left side of his brain. He has stated that he went 4 years without symptoms of Parkinson's disease. The transplantation of stem cells has enabled him to remain active. In another study, 5 Parkinson's disease patients were injected with a normal protein known as glial cell line-derived neurotrophic factor that stimulates adult stem cells of the brain. Within a year the patients demonstrated an average of 60% increased activity in physical coordination and lessening of symptoms of Parkinson's disease.
Stem cells are effective for those with Parkinson's disease when they become dopamine-producing nerve cells. One treatment method involves transplanting stem cells into target sites of the brain that need dopamine. Researchers cultivate stem cells from bone marrow making them very similar to nerve cells that produce dopamine. Because Parkinson's disease is caused by one type of cell failing to do its job, this disease is one of the best candidates for stem cell therapy.
Researchers have shown that dopamine-producing neurons can be generated from monkey stem cells and transplanted into the brains of monkeys suffering from Parkinson's disease with symptoms relieved and reversed. They have also shown that mouse stem cells can differentiate into neurons under certain specific conditions. Other research, being conducted at the National Institutes of Health, has demonstrated that rat stem cells grown in culture and transplanted into rats with Parkinson's disease will differentiate them into healthy, mature brain cells. These rats experienced some neurological recovery.
Parkinson's disease is a disorder of the central nervous system involving the brain and spinal cord. It is one of the conditions known as movement disorders. Parkinson's disease occurs when certain nerve cells in a part of the brain become impaired. A chemical substance called dopamine is made by certain cells in the brain. Dopamine carries messages that tell the body when and how to move, it allows for smooth, coordinated functions of the body's muscles. Parkinson's disease occurs when these cells either die or become damaged. When this happens there isn't enough dopamine to carry the messages and movement becomes very difficult. Symptoms of Parkinson Disease usually occur when 80% of the cells become damaged. Parkinson's disease is a chronic and progressive disease, it lasts for a long time and the symptoms get worse over time. There are approximately 1.5 million Americans with Parkinson's disease and it is estimated that 60,000 new cases are diagnosed each year. Parkinson's disease affects both men and women and shows no ethnic, social, economic or geographical boundaries. It usually occurs after age 65; however 15% of those diagnosed are under 50.
Doctors do not know what causes Parkinson's disease but believe it may be related to chemicals called free radicals that build up in the brain and damage the cells that make dopamine, toxins in the environment, genetic factors and faster-than-usual loss of the brain cells that make dopamine. Symptoms of Parkinson's Disease include tremors or shaking, slowness of movement such as shuffling, rigid limbs and trunk, poor balance and coordination and as time goes on Parkinson's Disease leads to other symptoms such as depression and anxiety, chewing and swallowing problems, speech changes, problems with urination and constipation, and sleeping problems. Diagnosis of Parkinson's disease is usually based on typical signs and symptoms. Blood tests and brain scans may be performed to rule out other conditions that have similar symptoms; however there is no specific test for Parkinson's disease. Treatment of Parkinson's disease includes medications that mimic dopamine and brain surgery is sometimes used in the later stages of the disease.

If you would like additional information on this type of therapy or where this therapy is currently being administered please do not hesitate to contact me at: or



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