really depends on what is wrong. Personally I have fought off terrible sinus infections with no Antibiotics by continously flushing out my sinuses with saline solutiona dn taking tons of vitamin c , garlic and inhaling steaming salt water. I used to need to take Antibiotics several time sper years but I ave not taken any in at least six years after dealing with a horrible candida problem I would have be almost dead before I would give in a take them.