It looks like Colosan is making use of the same concepts as Oxypowder. So they're probably similar products like Coke and Pepsi. Colosan is a powder, or something that you mix with water. Oxypowder is a pill. This difference might effect how it is delivered into the body. Remember, stomach acids are powerful and can break down or destroy a lot of things before they get to our intestines. At the very least? I know oxypowder is FDA certified. Checking a product against some kind of certification like the FDA, and checking the BBB.org to see if they have been doing good business is always a good thing to do. Here's some more info on oxypowder. http://www.candidablog.com/a-comprehensive-oxypowder-review.php