I tried Oxypowder a month or so ago and had good results (started at the end of Master-Cleanse and continued 2weeks on Oxypowder , then quit taking it). A couple of weeks later, I started to get constipated, so I tried the Oxypowder again. I got all gassy and bloated and got out no BM's whatsoever. I finally gave up on the Oxypowder and just gave myself a bag enema. Several weeks later, constipation AGAIN. This time, after thinking the thing through, I decided to do an enema BEFORE beginning the Oxypowder, thinking that the last time I must have been so plugged up that the Oxypowder was not able to work properly. Long story short, I have been up since the wee hours of the morning, running to the bathroom every hour or so because now the Oxypowder is working TOO well. Oh well, at least now I'm not constipated. Anyways, I think I will switch to taking the pills first thing in the morning, as opposed to taking them before bed, so as not to be up all night in the future. The instructions say to take the pills every other day, once your initial cleanse is completed, and to just continue taking the pills (till forever??). I'd really rather not take ANY pill for the rest of my life - I've read about how some people have taken the Oxypowder initial cleanse and no longer have bowel problems (and thus are able to discontinue the Oxypowder). If anyone has an Oxpowder story they'd like to share, it sure would be appreciated. I hate the thought of having to take Oxypowder for the rest of my life, just so I can go to the bathroom.