I am currently using Formula 722 for an anti-fungal as part of my rotational schedule. I decided to try it after reading about it on Karen Tripp's website about a 30 day cure. She obviously didn't have a systemic yeast problem so this did indeed work for her. It is also part of the candidiasis protocol program at the Modern Herbalist (I don't use that program or plan to, I just read about Formula 722 there as well)but they specifically state that unless you have a mild case, this will not work on it's own. I HAVE experienced a significant improvement in my condition over the past 6 months but I attribute that to the cumulative efforts of a strict diet, cleansing & the rotational use of varied anti-fungals, Formula 722 just being one among the arsenal :) After doing some research on both the product & the manufacturer, I decided to give it go as it is also very inexpensive so if I didn't feel it was effective, no great expense wasted!! Recently, on a forum (maybe even here somewhere) someone had posted about seeing a new naturopath or nutritionist who had reviewed her list of supplements, etc. Some things she discounted as a waste or uneccessary but she did note that the Formula 722 was a good thing to take. At the very least, I know it hasn't hurt me or set me back at all. I hope this helps answer any questions.