in honor of tony isaacs. enjoy your rest, sir.
here is how Oleander
Offsetting its value as a flowering shrub is oleander's invasive potential or presence in some areas. Although Oleander
is harmless to most pollinators it attracts, it is poisonous to people and pets. The plant produces oleandroside and nerioside, which are glycoside toxins that may be fatal. These toxins do not harm the leaf-eating Oleander
caterpillar (Syntomeida epilais Walker), but they make the caterpillars toxic to predatory birds. Wear gloves or wash your hands thoroughly after you prune oleander, particularly if the toxic sap gets on your skin. Do not burn the trimmings because the fumes are also toxic.
cancer cells run on glucose and glycogen. many have tried to starve their cancers unsuccessfully by restricting glucose only. recent advances in treatment have some using glucose restriction and some sort of a glycoside.
New Roles for Glycogen in Tumor Progression
Glycogen is a high-density glucose polymer, which provides organisms with an immediate source of glucose to support the cell’s energy requirements. Epithelial cells primarily store energy as glycogen, but until recently it has not been reported as a major fuel source for cancer growth. Hypoxia, which occurs in many cancers, results in glycogen synthesis and increased survival under stressed conditions. Recently, glycogen mobilization has been shown to play a role in the maturation and immune activity of dendritic cells (DCs) and in the proliferation and metastatic efficiency of cancer cells aided by the tumor microenvironment (TME). These studies indicate that glycogen plays an important role in glucose homeostasis and contributes to key functions related to tumor aggressiveness and the survival of cancer cells.
thanks tony. you are missed.