My experience with doxy was good, first when I take, many years ago, I have had herx whit very strong muscle twitches in the night, unfortunately I stoped to take it. I have try doxy for 3-4 time, I feld more better, but the time to take for better feeling was always longer. Last when I take doxy, I have the migration feeling to (befor not), whit doxy it was better. For me doxy is the best AB.