Colloidal Silver in action
Summary
Silver nanoparticles offer a possible means of fighting antibacterial resistance. Most of their antibacterial properties are attributed to their silver ions. In the present work, we study the actions of positively charged silver nanoparticles against both methicillin-sensitive Staphylococcus aureus and methicillin-resistantStaphylococcus aureus. We use aberration-corrected transmission electron microscopy to examine the bactericidal effects of silver nanoparticles and the ultrastructural changes in bacteria that are induced by silver nanoparticles. The study revealed that our 1 nm average size silver nanoparticles induced thinning and permeabilization of the cell wall, destabilization of the peptidoglycan layer, and subsequent leakage of intracellular content, causing bacterial cell lysis. We hypothesize that positively charged silver nanoparticles bind to the negatively charged polyanionic backbones of teichoic acids and the related cell wall glycopolymers of bacteria as a first target, consequently stressing the structure and permeability of the cell wall. This hypothesis provides a major mechanism to explain the antibacterial effects of silver nanoparticles on Staphylococcus aureus. Future research should focus on defining the related molecular mechanisms and their importance to the antimicrobial activity of silver nanoparticles.
HAADF-STEM micrographs of MRSA cells. (a) MRSA cells surrounded by AgNPs, with AgNPs smaller than 10 nm also being found inside of the cells. (b,c) (1) CWGs. (2) AgNPs interacting with WTAs and CWGs. MRSA cell micrograph shows a cell wall size of 32 nm. The Ag nanoparticle concentration is 23 ppm. (d) (3) Membrane destabilization (≈50 nm).
MRSA STEM images. (a) (1) WTAs and CWGs (≈3 nm). (b) (2) AgNPs interacting with CWGs. (3) Membrane destabilization (≈88 nm). (4) Cytoplasmic leakage. The Ag nanoparticle concentration is 23 ppm.
MSSA cell STEM image. (a) MSSA cell showing AgNP attachment on the cell wall. (b) High magnification STEM images of MSSA cell (1) wall teichoic acids (≈3 nm), (2) interaction of AgNPs with CWGs, (3) destabilization, (4) leakage of cytoplasmic material leading to bacterial cell lysis, (5) cytoplasm, (6) cytoplasmic membrane and (7) cell wall. The AgNP concentration was 11.5 ppm.
SOURCE: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685924/
several doctors trust the atomic particles colloids and they, have seen the same evidence that you and others have been presented with and are convinced that atomic particle colloidal silver is the best alternative to products that barely work.
Your opinion? Source? Proof?
However, if a study was done in the US ( highly unlikely because the institute that did the research would likely never receive another study from the pharmaceutical industry ), it would be highly expensive, costing 5 to 10 times the cost of the third world study.
Even the largest of settlements rarely dent the profits associated with the drugs involved: for example, the largest fine ever imposed on a drug company — July’s $3 billion judgment against GlaxoSmithKline (GSK) in part for illegally marketing the antidepressants Paxil and Wellbutrin and withholding data on the health risks of the diabetes medication Avandia — accounted for just 11% of associated revenue. Many other cases resulted in relatively smaller losses even when the fines were imposed as criminal penalties, as in the GSK case, and not just for civil law violations. Contrast such outcomes with those in most individual cases of fraud, in which all profits are typically confiscated as ill-gotten gains and the fraudster goes to prison.
A recent editorial
in the New England Journal of Medicine calls for change: levy large enough fines against drug companies for illegal behavior, so that the payouts can’t be dismissed as merely “the cost of doing business”; offer more protections for whistleblowers; and perhaps most importantly, file criminal charges against drug company executives for misconduct that could put them in prison.
- Why bother to have to do studies when they only have to pay a small percentage of the profits they make for damages.
However, atomic particle Colloidal Silver can be converted to Ionic Silver by adding a corrosive chemical.
But why would anyone want to do that, since the atomic particle Colloidal Silver is pure by its self?
Your opinion? Care to provide a source? Proof?