50k a day sounds like a lot. :o
Were you severely deficient before? Do you know what your Vitamin D level is at now?

*bump* If I take more than 1000iu per day I get a fat lip which hangs a round for 12 hours or more. 1000iu is about right for me.

So long as vitamin k2 is supplemented with it I do not believe you will develop toxicity. From my understanding d toxicity symptoms are k2 deficiency symptoms. My mega doses not only cleared my severe allergies but the k reduced my cholesterol on its own. I have had not one negative side effect from what I've done in two years. Only positive. Truly was a miracle for me. I'm not saying everyone will respond the same but for me it was life changing. I'm experimenting with Iodine now as well but I will never stop taking d3. I did drop my dose over June july and August to 30k a day because we were at the pool a lot.

Beatty57, I agree 100% after going down the orthomolecular route for a decade.

I think sunshine and high vitamin Cod liver oil is the best way to go.