princeofsin
Probiotics colonize the mucin layers that cover the intestinal walls, the finger-like extensions in the small intestine called villi (and microvilli), the crypts or gaps between the villi, the sack above the appendix called the cecum, the cells on the wall of the colon, and fecal matter as it forms in the colon. The sum of all these colonization events is called your I.P.C or Internal Probiotic Culture, the more extensive the better. So yes it can happen is you are not taking
Antibiotics .